We estimate trends in AMR rates and detect the emergence and potential spread of AMR pathogens in order to inform programmes that formulate guidelines for treatment and prevention of infections and prevention of AMR transmission
Our research in AMR started in 2011. The core of our activities include training, research and the provision of technical expertise in clinical microbiology, molecular biology, disease surveillance, One Health analytical epidemiology and One Health molecular biology. We set out to address the AMR problem from the One Health perspective in humans, animals and the environment. Therefore, our research team combines expertise and experience from the three sectors
We aim to improve the understanding of the AMR drivers and the nature of spread and persistence of AMR to develop and test different intervention models. Working towards a cost-effective, evidence-based policy that is relevant in health and agricultural systems in the region and serve as a model for resource-limited countries.
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Preparing for the Next Pandemic
By providing a platform for an Africa-led South-South-North smart partnership of unique world-class expertise, facilities and collaborations for AMR research and translation to impact on the health and livelihoods of communities within East, Central and Southern African countries. In Targeting influence on the trio of “Product-Practice-Policy” that will enhance community participation in the National/Regional Health Security. This programme will be delivered through four thrusts:
Addressing Use/Abuse of antimicrobials
Analysing and address factors and practices that lead to use/abuse of antimicrobials in Southern and East Africa
Mapping genomic epidemiology in AMR
identify diagnostic and genomic analytical approaches to map the genomic epidemiology of AMR; the sociological determinants and; the integrative modelling that lead to enhancing the determinants of the AMR and define potential solutions
AMR Policy Frameworks
Analysing the available AMR policy framework and assessing their impact in controlling AMR
Theme based intervention models
Developing, validating, and testing the functionality of theme-based interventions models, and evaluation of their performance
Research Question of the Programme
What are the best research and capacity building strategies needed to combat the onset and spread of AMR in health care, veterinary, fisheries and environment at the community level. Research topics include:
Enhancing knowledge and understanding of the ecology of resistant pathogens and resistant genes that can inform national and global strategies on AMR
Generating comprehensive high quality data on leading to development of integrated AMR initiatives that will address social and climatic Determinants of AMR
Attaining a holistic understanding of drivers of antimicrobial resistance within formal and informal healthcare and animal health care systems using a OH health approach that involves different disciplines and sectors
Develop effective surveillance systems that are well coordinated and complementary, using cost-effective and sustainable approaches and technologies for detection and management of human and animal AMR health risks at the community level
Improve approaches to antimicrobial development, marketing and environmental risk management as well as promoting better corporate social responsibility where investors and consumers can bring their own influence to bear
Improving judicious use of antimicrobial agents through promoting Infection Prevention and Control (IPC) and antimicrobial stewardship (AMS) programs
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